- Mercy Nurse
- Symptom Navigator
- Levitt Medical Library
- Health Information
- Body Guide
- Multimedia Encyclopedia
- In-Depth Health Reports
- Complementary & Alternative Medicine
- Drug Information Center
- Drug Interactions
- Wellness Tools
- Today's Medical News
- Pregnancy Health Center
- Recursos EspaÃ±oles De la Salud
- Enciclopedia Multimedia
- Centro de Information sobre el Embarazo
Leukemia is a type of cancer in which the body produces large numbers of abnormal (usually white) blood cells. About 28,500 new cases of leukemia are diagnosed each year. There are several types of leukemia, grouped as either acute (the diseases progresses rapidly) or chronic (the diseases progresses slowly). The most common leukemias are:
Signs and Symptoms
Signs and symptoms of leukemia include:
What Causes It?
Most causes of leukemia are not known. Several genetic and environmental factors are associated with childhool leukemia. The disease has also been linked to exposure to large amounts of high energy radiation (from nuclear bombs), occupational exposure to the chemical benzene, viral infections, and chemicals from cigarettes.
Who's Most At Risk?
Leukemia is linked to the following risk factors:
What to Expect at Your Provider's Office
If you or your child has symptoms associated with leukemia, see your health care provider. Your health care provider can make a diagnosis and help you determine which treatment or combination of therapies will work best.
Your health care provider will do a physical examination, checking for swelling in the liver, the spleen, and the lymph nodes, and will order certain laboratory tests. The bone marrow is examined for leukemia cells or to determine the type of leukemia. A lumbar puncture ("spinal tap") checks for leukemia cells in the fluid around the brain and spinal cord. Chest x-rays can reveal signs of the disease in the chest.
Some leukemias can be prevented by avoiding exposure to benzene, nicotine, or radiation.
Leukemia is an extremely complex disease. Treatment depends on the type of leukemia, certain features of the leukemic cells, the extent of the disease, and whether the leukemia has been treated before. Whenever possible, a patient with leukemia should be treated at a medical center that specializes in the disease.
Some of the drug therapies used to treat leukemia include the following:
Surgical and Other Procedures
Surgeries may include:
Complementary and Alternative Therapies
A comprehensive treatment plan for leukemia may include a range of complementary and alternative therapies. Individuals should educate themselves and keep all medical providers fully informed regarding any and all therapies they are using, both prescribed drugs and dietary supplements. While supplements and herbal therapies may be an important component of a comprehensive cancer care program, some supplements and herbs may interfere with conventional cancer care, and new research about these interactions is emerging every day. Work with a knowledgeable physician and inform all of your health care providers about any herbs and supplements you are using or considering using.
Nutrition and Supplements
Following these nutritional tips may help reduce symptoms:
You may address nutritional deficiencies with the following supplements:
Although few studies have examined the effectiveness of specific homeopathic therapies, professional homeopaths may consider the following remedies for the treatment of gastritis symptoms (such as nausea and vomiting) based on their knowledge and experience. Before prescribing a remedy, homeopaths take into account your constitutional type -- your physical, emotional, and psychological makeup. An experienced homeopath assesses all of these factors when determining the most appropriate treatment for an individual.
Homeopathy may help reduce symptoms and strengthen overall constitution and may help lessen the side effects of chemotherapy.
Acupuncture may alleviate symptoms. Acupuncture may help to enhance immune function, normalize digestion, and address disease conditions. For many patients and physicians, acupuncture has become one of the most widely used alternative interventions in cancer therapy support.
Repeated infections complicate most cases of leukemia. Kidney failure or impaired function and a decreasing number of neutrophils (a type of white blood cell) are also common complications. Treatments for leukemia can have serious side effects.
The prognosis for people with leukemia varies by the type of leukemia. ALL patients have the best prognosis, with a 5-year survival rate of 80%.
Patients with leukemia undergo extensive follow up care, including daily exams to check for infections and bleeding, weekly bone marrow biopsies after chemotherapy has begun, post remission chemotherapy, treatment for central nervous system conditions, and monitoring of urinary function.
Benchimol EI, Mack DR. Probiotics in relapsing and chronic diarrhea. J Pediatr Hematol Oncol. 2004;26(8):515-7.
Boros LG, Nichelatti M, Schoenfeld Y. Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases. Ann N Y Acad Sci. 2005;1051:529-42.
Brauner EV, Andersen CE, Anderson HP, Gravesen P, Lind M, Ulbak K, et al. Is there any interaction between domestic radon exposure and air pollution from traffic in relation to childhood leukemia risk? Cancer Causes Control. 2010; 21(11):1961-4.
Cabrera C, Artacho R, Gimenez R. Beneficial effects of green tea -- a review. J Am Coll Nutr. 2006;25(2):79-99.
Cheng TO. Can green tea protect against not only sunburn but also melanoma? Chin Med J (Engl). 2006;119(12):1056.
Das M, Sur P, Gomes A, Vedasiromoni JR, Ganguly DK. Inhibition of tumor growth and inflammation by consumption of tea. Phytother Res. 2002;16 Suppl 1:S40-4.
Dorchies OM, Wagner S, Vuadens O, et al. Green tea extract and its major polyphenol (-)-epigallocatechin gallate improve muscle function in a mouse model for Duchenne muscular dystrophy. Am J Physiol Cell Physiol. 2006;290(2):C616-25.
Eschenauer G, Sweet BV. Pharmacology and therapeutic uses of theanine. Am J Health Syst Pharm. 2006;63(1):26, 28-30.
Hollender A, Bjoro T, Otto Karlsen K, et al. Vitamin D deficiency in patients operated on for gastric lymphoma. Scand J Gastroenterol. 2006;41(6):673-81.
Jiang J, Slivova V, Sliva D. Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-kappaB signaling. Int J Oncol. 2006;29(3):695-703.
Kelemen LE, Cerhan JR, Lim U, et al. Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control study. Am J Clin Nutr. 2006;83(6):1401-10.
Kliegman. Nelson Textbook of Pediatrics, 19th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier. 2011.
Kormosh N, Laktionov K, Antoshechkina M. Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer. Phytother Res. 2006;20(5):424-5.
Laviano A, Muscaritoli M, Rossi-Fanelli F. Phase II study of high-dose fish oil capsules for patients with cancer-related cachexia: a Cancer and Leukemia Group B study. Cancer. 2005;103(3):651-2.
MacLean CH, Newberry SJ, Mojica WA, et al. Effects of omega-3 fatty acids on cancer risk: a systematic review. JAMA. 2006;295(4):403-15.
McCarty MF, Block KI. Toward a core nutraceutical program for cancer management. Integr Cancer Ther. 2006;5(2):150-71.
Miller MF, Bellizzi KM, Sufian M, et al. Dietary supplement use in individuals living with cancer and other chronic conditions: a population-based study. J Am Diet Assoc. 2008;108(3):483-94.
Polesel J, Talamini R, Montella M, et al. Linoleic acid, vitamin D and other nutrient intakes in the risk of non-Hodgkin lymphoma: an Italian case-control study. Ann Oncol. 2006;17(4):713-8.
Rakel RE, Bope ET. Conn's Current Therapy. Chronic Leukemias.Section 8. Philadelphia, PA: Elsevier Inc 2008.
Rubnitz J, Gibson B, Smith F. Acute Myeloid Leukemia. Hematology/Oncology Clinics of North America. 2010;24(1).
Rubnitz JE, et al. Acute mixed lineage leukemia in children: the experience of St. Jude Children's Research Hospital. Blood. 2009;113(21):5083-9.
Slater ME, Linabery AM, Spector LG, Johynson KJ, Hilden JM, Heerema NA, et al. Maternal exposure to household chemicals and risk of infant leukemia: a report from the Children's Oncology Group. Cancer Causes Control. 2011; 22(8):1197-204.
Wan XS, Ware JH, Zhou Z, Donahe JJ, et al. Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents. Int J Radiat Oncol Biol Phys. 2006;64(5):1475-81.
Wang HK. The therapeutic potential of flavonoids. Expert Opin Investig Drugs. 2000;9(9):2103-19.
Wayne A, Baird K, Egeler R. Hematopoietic Stem Cell Transplantation for Leukemia. Pediatric Clinics of North America. 2010;57(1).
Velicer CM, Ulrich CM. Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review. J Clin Oncol. 2008 1;26(4):665-73.
Review Date: 6/7/2012
Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.