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Lung diffusion testingDefinitionLung diffusion testing is used to determine how well oxygen passes from the air sacs of the lungs into the blood. The test measures the "diffusing capacity of the lung for carbon monoxide" or DLCO. Alternative NamesDiffusing capacity; DLCO testHow the Test is PerformedYou breath in (inhale) some gas containing a very small quantity of carbon monoxide, hold your breath for 10 seconds, then rapidly blow it out (exhale). The single exhaled gas is analyzed to determine how much carbon monoxide was absorbed during the breath. How to Prepare for the TestDo not eat a heavy meal before the test. Do not smoke for at least 4 - 6 hours prior to the test. If you use a bronchodilator or inhaler medications, ask your health care provider whether or not you can use them before the test. How the Test Will FeelThe mouth piece fits tightly around your mouth. Clips are put on the nose. Why the Test is PerformedThe test is used to diagnose the presence and extent of certain lung diseases. It may also be used to see how gases move the lungs into the bloodstream. Normal ResultsNormal test results depend on a person's age, sex, and height. What Abnormal Results MeanAbnormal results generally mean that gases do not move normally across the lung tissues. This may mean that lung diseases, such as interstitial fibrosis, sarcoidosis, asbestosis, and emphysema, are present. RisksThere are no significant risks. ConsiderationsOther pulmonary function tests may be done in combination with this test. ReferencesLamberto C, Nunes H, Le Toumelin P, Duperron F, Valeyre D, Clerici C. Membrane and capillary blood components of diffusion capacity of the lung for carbon monoxide in pulmonary sarcoidosis: relation to exercise gas exchange. Chest. 2004 Jun;125(6):2061-8. Mohsenifar Z, Lee SM, Diaz P, et al. Single-Breath Diffusing Capacity of the Lung for Carbon Monoxide: A Predictor of PaO2, Maximum Work Rate, and Walking Distance in Patients With Emphysema. Chest 123: 1394-1400.
Review Date:
8/3/2007 Reviewed By: Allen J. Blaivas, DO, Pulmonary, Critical Care, and Sleep Medicine, Department of Veteran Affairs, VA New Jersey Health Care System, East Orange, NJ. Review provided by VeriMed Healthcare Network. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-
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